Mogi-131 «iPhone»

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MOGI-131 is a potent, selective, and brain-penetrant GPR139 agonist with robust preclinical efficacy in depression, nicotine withdrawal, and motivational deficits. Its favorable pharmacokinetics and safety profile support progression toward first-in-human studies. As a tool compound, it will enable critical mechanistic dissection of GPR139’s role in reward, aversion, and mood regulation. mogi-131

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