Yes. If you are comfortable with PowerShell scripts, you can create two separate shortcuts.
While older versions of Windows relied on a universal keyboard command, Windows 11 handles things a bit differently depending on your hardware. 1. The Classic Graphics Shortcut (Intel Users) display orientation shortcut windows 11
If your computer uses Intel integrated graphics (common in laptops), you likely have built-in hotkeys enabled. display orientation shortcut windows 11
Are you trying to set up a layout, or just looking to fix a flipped screen right now? display orientation shortcut windows 11