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The film follows a six-member crew aboard the International Space Station who successfully capture a soil sample from Mars. The sample contains the first evidence of extraterrestrial life—a small, single-celled organism named "Calvin." As the crew nurtures and studies Calvin, it rapidly evolves into a highly intelligent, resilient, and deadly creature that begins to pick off the crew one by one. The film is a tense, claustrophobic thriller in the tradition of Alien , focusing on the terrifying consequences of humanity’s attempt to play with the unknown.