Impacted Sweat - Gland

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Impacted sweat glands range from a minor nuisance (heat rash) to a debilitating chronic condition (Fox-Fordyce Disease). Clinicians should suspect apocrine impaction (Fox-Fordyce) when a patient presents with intensely itchy, dome-shaped papules in the axillae or groin that flare with stress. While topical steroids and retinoids are first-line, refractory cases often require systemic retinoids or Botulinum toxin to restore quality of life. Further research is needed to fully elucidate the hormonal mechanisms driving this condition. impacted sweat gland