The episode explores Sheldon's struggles with social interactions and his difficulties in understanding why others might not share his enthusiasm for technology and science.
Scene release groups sometimes append the codec name to distinguish from x264 or x265 versions. For example:
Whether you're watching for the emotional connections to The Big Bang Theory or the classic Cooper family hijinks, "Pasadena" remains a standout episode in the series' history, currently holding a high interest among fans on Rotten Tomatoes . "Young Sheldon" Pasadena (TV Episode 2020) - IMDb
If you see openh264 in a video filename (e.g., Young.Sheldon.S03E16.OpenH264.mkv ), it simply indicates:
Regarding the specific episode you're asking about, "Young Sheldon S03E16 OpenH264," I assume you're referring to Season 3, Episode 16 of the show.
The final scene, which shows Sheldon standing in the Caltech cafeteria, actually used the original set from The Big Bang Theory .