Skip to Content

Digidata 1550b Plus Humsilencer | Free Forever

Unlike standard notch filters, HumSilencer is not a filter. It subtracts noise in real-time without causing signal distortion, such as phase shifts or amplitude attenuation.

The Digidata 1550B plus HumSilencer provides a cost-effective, non-invasive alternative to heavy Faraday cages for many intracellular and patch-clamp recordings. By adaptively cancelling 50/60 Hz hum at the digitizer input, it preserves signal fidelity while reducing lab infrastructure constraints. Molecular Devices could implement HumSilencer as a firmware upgrade for existing 1550B units (using external reference input) or as a new model: Digidata 1550B-HS. digidata 1550b plus humsilencer

The Digidata 1550B serves as the interface between biological preparations (via amplifiers) and the computer. It digitizes analog signals for storage and analysis. Unlike standard analog-to-digital converters, the 1550B is engineered specifically for the rigorous demands of patch-clamp and intracellular recording, where signal integrity is paramount. Unlike standard notch filters, HumSilencer is not a filter

The device is widely used with Axon Instruments patch-clamp amplifiers, such as the MultiClamp 700B or Axopatch 200B, to ensure clean data acquisition even in electrically noisy environments. Axon Digidata 1550B Low-Noise System plus HumSilencer By adaptively cancelling 50/60 Hz hum at the

The Digidata 1550B features a proprietary real-time noise elimination circuit called HumSilencer .